Premature ejaculation is ejaculation (painful orgasm) when a man ejaculates with a woman. It is the most common sexual disorder, affecting approximately 40% to 50% of men of all age. Ejaculation is the most common sexual problem for men in the UK.
This medicine is only approved for use in men and is not suitable for use in women. This medicine should be used only if clearly needed for a woman's life.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. This medicine is best taken when pain is very difficult to control.
This medicine is best taken with food.
Your doctor may adjust the dose or suggest an alternate treatment. If this is not possible, tell your doctor before having any sexual activity.
This medicine should not be used in patients with a history of cardiovascular diseases, especially uncontrolled hypertension or with a prior history of stroke or heart attack.
Before taking this medicine, inform your doctor if you have any liver, kidney, or heart problems. This medicine is not suitable for use in pregnant or breast-feeding. This medicine should not be used in patients with prostate gland. If you are pregnant or breast-feeding, discuss the risks and benefits with your doctor.
Before using this medicine, tell your doctor if you are allergic to any other medicines, foods, preservatives or dyes, or if you have any disease or deformity of your penis. This medicine may increase the risk of blood clots, stroke or high blood pressure. If you have any unexplained vaginal bleeding or sudden pain or discharge from your pelvic area while using this medicine, stop and seek medical attention.
This medicine can cause undesired side effects. For further information, contact your doctor.
This medicine may increase the sensitivity of the skin or nails. If this happens, it is likely that you need to use a special product.
This medicine may cause pain and redness. To avoid this, avoid smoking and use painkillers (pain relievers like ibuprofen or paracetamol) with an anti-inflammatory effect.
If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
This medicine may increase the sensitivity of the skin. If you are allergic to any other medicines, ask your doctor about all the inactive ingredients in this medicine (prescription or OTC drugs).
This medicine may rarely cause changes in your blood cells, such as an increase in the number of abnormal (worsened) white blood cells (neutropenin, basic cellular growth factors) and thrombocytopenia (platelet count less than 3,000/mm³). Also, a decrease in platelet count can increase the risk of haemolytic anaemia (low platelets in the blood) and thrombocytopenia (low platelets in the blood).
Keep all medicines out of the sight and reach of children.
This product has been prescribed for you.This medicine may be used for purposes not listed in the included product.
Inform your doctor if any of the following adverse effects occur. If they do not disappear or become worse, notify your doctor immediately.
Oftentimes, this drug can cause serious (rarely fatal) bleeding from the penis.
Approximately 80% of women in the United States are not using birth control pills because they are considered "high risk." This percentage may be higher if you have:
Although estrogen cream has been shown to reduce the risk of endometrial cancer by about 50%, this is not clear as this is an older study. This is a very small study. The authors of the study (Eldegene) were the only participants who were randomized to receive estradiol cream (the same as the study) for 2 years or less.
The main finding of the study was that in women who used estradiol cream for 2 years, the risk of endometrial cancer was reduced by about 50%. This was not statistically significant compared to the placebo. The authors also noted that the risk reduction was not associated with the duration of use, however the risk reduction was not statistically significant at the 2-year and 4-year follow-up.
The authors noted that this study is not a "randomized placebo-controlled trial," but rather a "randomized controlled trial of estradiol cream," and that this is "a small, double-blind, randomized study of estradiol cream in women with a history of endometrial cancer."
The researchers noted that the risk of endometrial cancer was reduced in women using estradiol cream for 2 years, but not in women who were not using estradiol cream. This is because estradiol has a higher estrogenic activity than the other estrogens, and this is because estradiol also has the opposite effect of the estrogenic activity of the other estrogen. Estrogen can reduce the growth and survival of the endometrial lining.
The researchers also noted that this was not a randomized, placebo-controlled trial, and that this was a small, double-blind, randomized study of estradiol cream for 2 years. The study was done at the University of California, San Francisco, and the results have not been published.
Estradiol cream is applied topically every day on the skin. It is used to treat the symptoms of estrogen-sensitive and -resistant endometrial cancer. Estrogen is an estrogen hormone. When estrogen is not effective, it does not cause disease.
In clinical trials, the most common side effect associated with the use of estradiol cream is the spotting on the breasts, especially in the lower belly and in the thighs and at the hips, or between the knees. This may be indicative of endometrial cancer, or it may indicate that you may need to stop taking the medication altogether.
The other side effect associated with estradiol cream is the vaginal discharge, especially on the vulva. It can be associated with the use of estrogen-containing products, such as creams, gels, and patches.
Because of this side effect, the doctors prescribe it as "one-off" estrogen cream. If you continue taking estrogen, your doctor may adjust your dose or stop the use altogether.
Estradiol cream has a very small risk of adverse events when used as directed. There are a few risks associated with this use, but the risks of this medication should be considered in menopausal women, as it may decrease the amount of estrogen absorbed from the skin. In women who have a normal monthly menstrual period, there is a small increase in estrogen levels. However, if this happens, it is very unlikely that the medication will cause any serious adverse effects.
There is a slight increase in estrogen levels after menopause. When this occurs, the body has been advised to take the medication as directed.
If you are taking estrogen medication to treat the symptoms of menopause, you are advised to use estradiol cream as directed. Do not take this medication in a place that is not designed to be ingested, such as a kitchen teaspoon, or a cup of coffee. If you are taking the medication to treat your condition, you should avoid using it with foods that have high estrogenic activity.
Estrace Vaginal Cream (EUG-SEM) 0.01% is a vaginal cream containing estradiol which is an estrogen that is used in women who are experiencing vaginal dryness and vulvar irritation. It contains the active ingredients estradiol, desogestrel and luteinizing hormone. It is applied to the vagina and works by stimulating the production of the hormone progesterone in the body. Estrace vaginal cream contains the active ingredients estradiol, desogestrel and luteinizing hormone.
Uses
Estradiol Vaginal Cream is used to treat symptoms of vaginal dryness and irritation including itching, irritation, burning, and odor.
Ingredients
Estradiol is a synthetic estrogen hormone that is a part of the natural hormonal system of the body.
Desogestrel is a type of hormone that is produced by the pituitary gland in the brain.
Luteinizing hormone (LH) is a natural hormone produced by the adrenal glands and is also produced in the same way by the pituitary gland in the liver.
These hormones are responsible for the development of vaginal dryness and irritation.
LH also stimulates the production of progesterone, which in turn, stimulates the growth of the lining of the womb (womb).
Dosage
The recommended dose of estradiol is one 0.1% cream applied to the vagina twice a day for 14 days.
For a 2-day regimen, the recommended dose is one 0.01% vaginal cream applied to the vagina twice a day for 14 days.
Side effectsPrecautions
Side effects of estradiol are not known to be harmful. If you experience any severe or persistent side effects such as chest pain, shortness of breath or swelling in the breasts, breast lumps, breast lumps, breast lumps, breast lumps, breast lumps, breast lumps, breast lumps, swelling of the breasts, breast lumps, vaginal discharge, breast lumps, vaginal itching or discharge, vaginal bleeding, or itching of the vulva, stop using the product and see a doctor immediately.
Storage
Store the product at room temperature and keep it out of the reach of children.
WarningsEstradiol contains the active ingredients estradiol, desogestrel and luteinizing hormone.
Directions
Use the cream as directed by your doctor.
Inactive ingredients
Active ingredients:Estradiol Vaginal Cream contains the active ingredients estradiol, desogestrel and luteinizing hormone.
Inactive ingredients:
Each ointment contains the active ingredients estradiol, desogestrel and luteinizing hormone.
ContraindicationsAdverse effects
Side effects may include breast tenderness, swelling or fluid retention.
If you have any of the following serious health problems, including a known hypersensitivity to estradiol, estradiol or estradiol propionate, or estradiol sulfate, stop using this product and contact your doctor immediately:
Pregnancy and lactation: This product is not recommended during pregnancy. Women who are breastfeeding should not use this product. Breastfeeding mothers should not use this product.
References
Read this Patient Information leaflet if you have any further questions regarding the use of this medicine.Estradiol contains estradiol, a progesterone-like endo-progesterone which is used to treat menopause symptoms (such as painful periods, vaginal dryness, and/or itching). Estradiol may also be used for prevention of vaginal atrophy and/or endometriosis. It is a progesterone that is produced by the progesterone-producing glands of the ovaries and is produced in the ovaries by the progesterone-producing (or progestogen-producing) cells in the ovary. It is not synthesized by the progestogen-producing cells in the ovary. Estradiol is present in breast milk, but is not present in breast-fed infants or children. Estradiol is excreted in the breast milk and is not recommended for use in children under 14 years of age.
Take Estradiol orally as directed by your doctor or as your doctor has told you. Shake the bottle well before each dose to ensure that all of the drug is evenly distributed.
Take this medication by mouth with or without food as directed by your doctor, usually once daily.
An overdose of Estradiol may be serious and be life threatening. Symptoms of overdose may include painful menstrual periods, heavy menstrual bleeding or spotting, and/or heavy menstrual periods.
This is not a complete list of all side effects and others may occur. If you experience any of the symptoms listed here, talk to your doctor or pharmacist.
Keep this medication with the provided medicine and all other medicines you are taking as they are all medicines that you should not take more than once per day. In the event of a serious overdose develop, you should get medical help immediately.
Tell your doctor or pharmacist of all the medicines, vitamins, and nutritional supplements you take or plan to take without stopping. This includes prescription and over-the-counter medicines and herbal supplements. It is important that they tell you about any other health problems you have and that you are taking any of the following:
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